Molecular detection of murine gammaherpesvirus 68 (MHV-68) in bats from Mexico
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چکیده
منابع مشابه
Murine gammaherpesvirus (MHV-68) transforms cultured cells in vitro.
Human dermal fibroblasts and mouse NIH/3T3 cells acquired the transformed phenotype ('criss-cross' pattern of growth) after infection with ultraviolet-irradiated murine gammaherpesvirus (MuHV-4 strain 68; MHV-68). These cells with changed phenotype could be serially cultured for 5-6 passages (35-40 days), and then they entered into crisis and most of them died. In a small number of cultures, ho...
متن کاملMurine Gammaherpesvirus (MHV-68) Transforms Cultured Cells in vitro
Human dermal fibroblasts and mouse NIH/3T3 cells acquired the transformed phenotype (‘criss-cross’ pattern of growth) after infection with ultraviolet-irradiated murine gammaherpesvirus (MuHV-4 strain 68; MHV-68). These cells with changed phenotype could be serially cultured for 5–6 passages (35–40 days), and then they entered into crisis and most of them died. In a small number of cultures, ho...
متن کاملGlycosaminoglycan Interactions in Murine Gammaherpesvirus-68 Infection
Glycosaminoglycans (GAGs) commonly participate in herpesvirus entry. They are thought to provide a reversible attachment to cells that promotes subsequent receptor binding. Murine gamma-herpesvirus-68 (MHV-68) infection of fibroblasts and epithelial cells is highly GAG-dependent. This is a function of the viral gp150, in that gp150-deficient mutants are much less GAG-dependent than wild-type. H...
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Herpesviruses are a large group of DNA viruses infecting mainly vertebrates. Murine gammaherpesvirus 68 (MHV68) is often used as a model in studies of the pathogenesis of clinically important human gammaherpesviruses such as Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus. This rodent virus appears to be geographically widespread; however, its natural transmission cycle is unknow...
متن کاملTranscription program of murine gammaherpesvirus 68.
Murine gammaherpesvirus 68 (MHV-68 [also referred to as gammaHV68]) is phylogenetically related to Kaposi's sarcoma-associated herpesvirus (KSHV [also referred to as HHV-8]) and Epstein-Barr virus (EBV). However, unlike KSHV or EBV, MHV-68 readily infects fibroblast and epithelial cell lines derived from several mammalian species, providing a system to study productive and latent infections as ...
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ژورنال
عنوان ژورنال: Acta virologica
سال: 2020
ISSN: 1336-2305
DOI: 10.4149/av_2020_412